Nutrition, Physiological Regulation and Major Human Diseases


Langue d'enseignement : Anglais
Crédits ECTS: 3


  • Heures d'enseignement dispensées à l'étudiant : 24 heures
  • Temps de travail personnel : 66 heures

Objectifs et compétences

Objectifs :

Major chronic human diseases such as diabetes and cardiovascular pathologies are characterized by interplay between genetic background and life style with an important nutritional component. In the extreme case derangements may lead to the “metabolic syndrome” with consequences on glucose homeostasis and cardiovascular organs. The recent increase in obesity and nutrition-related disease further underscores the necessity to understand the basis of the impact of nutrition/life style on health.

This course will provide participants with models of normal and altered nutrition homeostasis and paradigms to study their influence in animal models. The course will focus on nutrition signalling, integration, short-term experimental effects and long-term epidemiology, from the point of view of the whole body, organs and down to the cellular and molecular level.

General Instructional Objective (GIO):

During this course student will learn about:

◦ Nutrition sensing, energy repartition and homeostasis

◦ Basic concepts of molecular, cellular and integrative aspects in nutrition homeostasis and cardiovascular function

◦ Current animal and cellular models used in such studies

◦ How to read, understand and integrate corresponding research results

◦ Explore the field through examples of defined pathologies and molecules which have positive or negative human health benefits as well as therapeutic approaches.

Specific Behavioral Objectives (SBO):

Students will receive

- An integrative view how major vital functions are regulated and how set-points are defined in physiological settings and influenced or changed by nutritional status.

- Information about experimental and therapeutic approaches as well as molecular effects of nutrients and drugs.

- Elementary idea of the genetic landscape that influences the systems.

Organisation pédagogique

le mode de fonctionnement de l'UE est présenté au début des enseignements

Contrôle des connaissances

Session 1

Présentation orale (coeff. 0,6)

Projet (coeff. 0,4)

Session 2

Présentation orale (coeff. 0,6)

Projet (coeff. 0,4)

Lectures recommandées

l'ensemble des références bibliographiques est communiqué au début des enseignements

Responsable de l'unité d'enseignement

Jochen Lang


la composition de l'ensemble de l'équipe pédagogique est communiquée au début des enseignements